Mass Spectrometry Analysis—Quadrupole-Time-Of-Flight (Qtof) Mass Spectrometer

Mass spectrometry has become invaluable in a wide range of fields and applications, including proteomics. The development of high throughput and quantitative MS proteomics workflows has expanded the scope of protein structure, function, modifications, and overall protein dynamics. In addition, MS has been widely used in metabolomics and glycomics analysis. Creative Proteomics is equipped with advanced mass spectrometers to support your experiments in academia or industry with the professional mass spectrometry-based analysis described above.

Name of the Instrument/Technicial Service

Quadrupole-Time-Of-Flight (Qtof) Mass Spectrometer

Introduction

The SCIEX TripleTOF^™ 5600 System is an innovative breakthrough in LC-MS2 performance that uniquely integrates comprehensive qualitative exploration, rapid profiling, and high-resolution quantitation workflows on a single platform. It combines the highest sensitivity detection, high-resolution with at least 5× better acquisition speed, and stable ~1 ppm mass accuracy over days of acquisition.

Summary

Quadrupole-time-of-flight (QTOF) mass spectrometers are high mass accuracy and high resolution instruments ideal for peptide sequencing in the Information Dependent Acquisition (IDA) mode. Their high resolution is useful for determination of charge state and protein mass measurements in addition to accurate mass determination of biological compounds.

Feature Highlights

1. High resolution at unparalleled speed-up to 40,000 FWHM with 10 msec accumulation time 2. EasyMassTM Accuracy without continuous recalibration-over 50 hours of continuous LC/MS operation provides <2 ppm RMS 3. SmartSpeedTM 100Hz Acquisition delivering high-resolution for high-speed chromatography-up to 100 spectra in a second or 50 spectra in a second while maintaining intelligent real-time data filtering (IDA). 4. Most sensitive high resolution system-lowest limits of quantitation (LOQ) for a high resolution system and equivalent to high-performance triple quads. 5. MS/MSALL with SWATH^™ Acquisition enabling comprehensive MS/MS quantitation in proteomic.

Creative Proteomics offers you Quadrupole-Time-Of-Flight (Qtof) Mass Spectrometer-based mass spectrometry services to help you solve your research problems related to proteomics, metabolomics, lipidomics, and more. If you are interested, please contact us directly.