Proteomics Analysis—Bruker maXis-II ETD ESI-qTOF

Proteomics research is not only essential for exploring the mysteries of life but can also be of great benefit to human health. Proteomics research is a feature of the post-genetic era in the life sciences. Creative Proteomics can accurately identify and quantify proteins in biological systems by mass spectrometry. We are well equipped to provide Bruker maXis-II ETD ESI-qTOF-based proteomics analysis services.

Name of the Instrument/Technicial Service

Bruker maXis-II ETD ESI-qTOF

Introduction

Specifications 1. Bruker's maXis-II ETD ESI-QqTOF instrument is equipped with Dionex Ultimate-3000 LC system 2. Database system for proteomics project management (ProteinScape 3.1, MASCOT) 3. Sub-ppm mass accuracy (<1 ppm) 4. Mass resolution > 80,000 (isotopic resolution even for proteins > 40 Kda 5. Applications include LC-MS/MS (with CID and ETD capabilities) analysis of complex protein/peptide and small molecules mixtures, mass analysis of large non-covalent protein systems

MANUFACTURER: Bruker

MODEL: Bruker maXis II ETD

Summary

Bruker's maXis-II ETD ESI-QqTOF instrument is equipped with Dionex Ultimate-3000 LC system. The platform combines latest hardware innovations in TOF technology with unique software packages (including ProteinScape 3.1 for proteomics project management) that deliver sub-ppm mass accuracy and up to 80,000 mass resolution. Key applications include LC-MS/MS (with CID and ETD capabilities) analysis of complex protein/peptide and small molecules mixtures, mass analysis of large non-covalent protein systems.

Applications

• Antibody Characterization - Intact and Subunit Analysis Enhanced resolution and mass precision for greater confidence in subunit measurements • Complex Protein Mixture Superb dynamic range (5 orders of magnitude) for the analysis of complex protein mixture • Native Mass Spectrometry (optional) The High Mass Option enables analysis of native protein complexes and ADC's • Robust LC-ETD capabilities For Top Down Sequence Confirmation on an LC timescale

The dedicated Creative Proteomics team can provide our clients with proteomics analysis services based on Bruker maXis-II ETD ESI-qTOF. If this is of interest to you, please feel free to contact us.