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Target Protein Characterization Service—800 MHz Bruker Avance III NMR

Creative Proteomics provides protein analytical support, from method development and fit-for-purpose validation to process/cleaning validation and sample analysis, as well as API, finished product, and impurity analysis. We specialize in a wide range of analytical assay technologies to support protein characterization and the development of recombinant proteins and peptide therapeutics.

Name of the Instrument/Technicial Service

800 MHz Bruker Avance III NMR

Introduction

Available probes:  1. Biomolecular solid state (HCN) MAS probes at a variety of rotor sizes (1.3 mm, 1.9 mm, 2.5 mm, 3.2 mm), and with options for increased salt tolerance 2. Broadband solid state (HX) MAS probe with 4 mm rotor size 3. Solution state TXI probe (1H inner coil, 13C/15N outer coil) Temperature range: -60℃ to 120℃, depending on probe

MANUFACTURER: Bruker

Summary

The 800MHz Bruker AVANCE III spectrometer offers outstanding resolution and is the crown jewel in the NMR Centre's inventory. This instrument is primarily used to study the structure and function of membrane proteins, with secondary focusses including the high-sensitivity detection of quadrupolar nuclei and high-resolution applications to small molecules and soluble proteins. The spectrometer is equipped with 4 RF channels and 3 high power RF amplifiers.

Creative Proteomics offers an 800 MHz Bruker Avance III NMR-based target protein characterization service that can be applied to APIs, finished products, and impurity analysis. If you are looking for technical support in this area, please contact us directly.

For research use only, not intended for any clinical use.

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