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Mass Spectrometry Analysis—Bruker micrOTOF with Agilent 1290 UHPLC

Mass spectrometry has become invaluable in a wide range of fields and applications, including proteomics. The development of high throughput and quantitative MS proteomics workflows has expanded the scope of protein structure, function, modifications, and overall protein dynamics. In addition, MS has been widely used in metabolomics and glycomics analysis. Creative Proteomics is equipped with advanced mass spectrometers to support your experiments in academia or industry with the professional mass spectrometry-based analysis described above.

Name of the Instrument/Technicial Service

Bruker micrOTOF with Agilent 1290 UHPLC

MANUFACTURER: Bruker

Summary

The micrOTOF is an ESI instrument with a time-of-flight (TOF) detector. The ESI source is a "gentle" ionization method, which makes it possible to analyze extremely large molecules such as proteins. The TOF mass analyzer gives high mass accuracy (<5 ppm) and resolution (10,000) for confirmation of molecular formula and accurate protein/peptide fragment assignment. The Agilent 1290 UHPLC delivers solvent flow rates between 10 microliters and 1000 microliters per minute, appropriate for typical analytical HPLC analyses as well as rapid high-performance UHPLC protocols. The micrOTOF is regularly used for evaluating recombinant proteins, providing accurate mass for novel organic synthesis products, quantitation of known metabolites, and for biophysical studies such as hydrogen-deuterium exchange of proteins.

Creative Proteomics offers you Bruker micrOTOF with Agilent 1290 UHPLC-based mass spectrometry services to help you solve your research problems related to proteomics, metabolomics, lipidomics, and more. If you are interested, please contact us directly.

For research use only, not intended for any clinical use.

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