Proteomics Laboratory Services
Proteomics Laboratory Services
The Creative Proteomics service team can perform a complete Bruker UltrafleXtreme-based analysis of the proteins in your samples. Our scientists will meet with you throughout the project, from initial planning to delivery of a comprehensive data package, to ensure that your objectives are met.
For protein QC, an intact mass analysis is highly recommended to check both integrity and identity of the protein of interest. Top down-sequencing is a crucial QC parameter to ensure that the target protein is highly pure without any degradation at the N- or C-terminus.
MANUFACTURER: Bruker
Matrix-assisted laser desorption/ionization (MALDI) is a soft ionization processes due to its capacity to transfer a moderate excess of energy to the analyte, which is crucial for fragile and non-volatile compounds such as proteins. MALDI is an ionization process from a solid phase: the protein of interest is dispersed in a saturated solution of a small aromatic molecule called matrix and the whole is co-crystallized by evaporation of the solvent. The solid phase obtained is irradiated, resulting in desorption of the ions. In MALDI, proteins mainly result in singly-charged or doubly-charged ion species. One of the main advantages is that the sample droplets can be prepared rapidly on the metal target, allowing the analysis of a large number of soluble or membrane proteins in a very short time.
Creative Proteomics' Bruker UltrafleXtreme-based protein analysis services can help deepen your scientific progress. If you are interested in this, please contact us directly.
For research use only, not intended for any clinical use.