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Proteomics Analysis—Orbitrap Exploris 480 (Thermo Scientific)

Proteomics research is not only essential for exploring the mysteries of life but can also be of great benefit to human health. Proteomics research is a feature of the post-genetic era in the life sciences. Creative Proteomics can accurately identify and quantify proteins in biological systems by mass spectrometry. We are well equipped to provide Orbitrap Exploris 480 (Thermo Scientific)-based proteomics analysis services.

Name of the Instrument/Technicial Service

Orbitrap Exploris 480 (Thermo Scientific)

Introduction

Most importantly, the FAIMS-PRO device adds a new dimension of selectivity. The application of FAIMS leads to a reduction of chemical noise, leading to better signal to noise ratios. The instrument has to be cleaned at intervals of about 6 months. The FAIMS-PRO device has to be cleaned every 3 weeks.

MANUFACTURER: Thermo Fisher Scientific

Summary

The Mass Spectrometry Facility operates 5 OrbiTrap Exploris 480 mass spectrometer (ThermoFisher), which are used to analyze the major part of the submitted samples. This mass spectrometer uses a high-capacity transfer tube for maximum ion loading, an electrodynamic ion funnel that accommodates and transmits ions over a broader mass range, and a high-field Orbitrap mass analyzer with a resolution of 480000 (FWHM) at m/z 200. The Advanced Peak Determination (APD) algorithm significantly increases the number of precursors available for data-dependent analysis, which in turn results in more MS/MS spectra, and peptide identifications.

The dedicated Creative Proteomics team can provide our clients with proteomics analysis services based on Orbitrap Exploris 480 (Thermo Scientific). If this is of interest to you, please feel free to contact us.

For research use only, not intended for any clinical use.

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