Proteomics Laboratory Services
Proteomics Laboratory Services
Proteomics research is not only essential for exploring the mysteries of life but can also be of great benefit to human health. Proteomics research is a feature of the post-genetic era in the life sciences. Creative Proteomics can accurately identify and quantify proteins in biological systems by mass spectrometry. We are well equipped to provide Thermo LTQ Orbitrap Velos ETD with Dionex UltiMate 3000 Nano-flow 2D LC System-based proteomics analysis services.
MANUFACTURER: Thermo Fisher Scientific
The Thermo LTQ Orbitrap Velos ETD with Dionex UltiMate 3000 nano-flow 2D LC system is a hybrid mass spectrometer that incorporates a linear ion trap and a high-resolution Orbitrap mass analyzer.
1. The linear ion trap permits selection and fragmentation of precursor ions of interest, and the Orbitrap performs Fourier-transform high-resolution analyses of the precursor and fragment ions. 2. Fragmentation capabilities include collisional ion activation (CID and HCD) and electron-based ion activation, electron-transfer dissociation (ETD). 3. The HCD cell in the LTQ facilitates quantitation of isobarically-labeled peptides for differential protein expression analysis or other applications requiring tandem mass tags (e.g. TMT or iTRAQ). 4. The ETD option is used for phosphopeptide analysis. 5. Peptide fragments generated by ETD provide complementary information to the conventional CID-generated information which is critical in post-translational modification (PTM) analysis and de novo sequencing. 6. The Dionex UltiMate 3000 nano-LC system can operate in both 1D and 2D LC mode, where the 2D LC mode facilitates separation of complex mixtures through two orthogonal separation approaches: reverse phase and strong cation exchange.
The dedicated Creative Proteomics team can provide our clients with proteomics analysis services based on Thermo LTQ Orbitrap Velos ETD with Dionex UltiMate 3000 Nano-flow 2D LC System. If this is of interest to you, please feel free to contact us.
For research use only, not intended for any clinical use.